OSCAR
Obesity Related Colorectal Adenoma Risk Study
Professor Colin Rees – South Tyneside and Sunderland NHS Foundation Trust
The OSCAR study is a prospective multi-centre cross sectional study looking at the association between obesity, Non-alcoholic Fatty Liver Disease (NAFLD) and colorectal adenomas.
Status: Data analysis/reporting
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About

Obesity has been shown to be associated with colorectal adenomas (pre-cancerous polyps). Non-alcohol Fatty Liver Disease (NAFLD) has been shown in Eastern Asian countries to also be associated with colorectal adenomas. In this study, we aim to assess the association between obesity and NAFLD with colorectal adenoma in a UK population. Information gathered in this study includes patient's medical history, medication history, family history, lifestyle (smoking and alcohol consumption habits), as well as height/ weight/ waist circumference measurements. We aim to tease out the association between obesity, NAFLD and colorectal adenomas, and to develop a risk model based on these factors to predict the presence of colorectal adenomas.

Where
Opened sites:
  • South Tyneside District Hospital
  • Sunderland Royal Hospital
  • North Tees University Hospital
  • Freeman Royal Hospital
  • Kettering General Hospital
  • James Cook University Hospital
  • Royal Bolton Hospital
  • University Hospitals of Morecambe Bay
  • Gloucestershire Royal Hospital
  • Lancashire Teaching Hospitals
  • Mid Cheshire Hospitals
  • Blackpool Teaching Hospitals
Who
Study Sponsor:
  • South Tyneside and Sunderland NHS Foundation Trust
Funded By:
  • Norgine
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