COLO-COHORT
Colorectal Cancer Cohort Study
Professor Colin Rees – Newcastle University & South Tyneside and Sunderland NHS Trust
COLO-COHORT aims to develop a “risk stratification tool” to help identify which patients are at highest risk of having adenomas or bowel cancer. We will also explore the significance of the gut bacteria composition in patients with adenomas or cancer to help inform this risk model. Additionally we will develop a large platform of patients who consent to be contacted for future research.
Status: Recruitment active
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About

COLO-COHORT, which is funded with a £1.25 million Guts UK Parabola Foundation grant, aims to recruit 10000 patients undergoing colonoscopy as part of ​the Bowel Cancer Screening Programme (BCSP​) or due to symptoms. Participants will be asked to fill in a health questionnaire and have their height, weight and waist circumference measured. They will also receive blood tests and stool tests, depending on the indication for their colonoscopy. The results of the colonoscopy and any samples taken will be collated. Patients will receive a patient experience questionnaire or food frequency questionnaire.

Additionally 10000 patients from the North of England will also be consented to be contacted for future studies with some of the information above collected.

How
Information for Patients:

This study will be rolled out to sites within the North East by Autumn 2020. If you are interested in participating in this study, and if the study is open at your local hospital, please contact a member of your local research team.

Where
Opened sites:
  • South Tyneside and Sunderland NHS Foundation Trust
  • North Tees and Hartlepool NHS Foundation Trust
  • Kettering General Hospital NHS Foundation Trust
  • Bolton NHS Foundation Trust
  • South Tees Hospitals NHS Foundation Trust
Opening sites:
  • Northumbria Healthcare NHS Foundation Trust
  • Hull University Teaching Hospitals NHS Foundation Trust
  • Gloucestershire Hospitals NHS Foundation Trust
  • West Hertfordshire Hospitals NHS Trust
Who
Researchers:
  • Professor Colin Rees
  • Professor Linda Sharp
  • Professor Mark Hull
  • Dr Suparna Mitra
  • Dr Laura Neilson
  • Dr Kyle Montague
  • Mr John Whelpton
Study Sponsor:
  • South Tyneside and Sunderland NHS Foundation Trust
Funded By:
  • Guts UK Parabola Foundation grant
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